TIMD4 Protein (AA 25-314) (His tag)
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- Target See all TIMD4 Proteins
- TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 25-314
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TIMD4 protein is labelled with His tag.
- Purpose
- Human TIM-4 Protein
- Sequence
- Glu25-Gln314
- Characteristics
- Recombinant Human TIM-4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu25-Gln314.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4) (AA 25-305) protein (His tag)
TIMD4 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4) protein (His tag)TIMD4 Origin: Mouse Host: HEK-293 Cells Recombinant > 94 % as determined by SDS-PAGE
T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4) (AA 25-314) protein (His tag)Crystallography grade TIMD4 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4) (AA 23-279) protein (His tag)Crystallography grade TIMD4 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4) (AA 25-378) protein (rho-1D4 tag)Crystallography grade TIMD4 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4) (AA 23-343) protein (rho-1D4 tag)Crystallography grade TIMD4 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))
- Alternative Name
- TIM-4 (TIMD4 Products)
- Synonyms
- RGD1564516 Protein, MGC99322 Protein, TIMD4 Protein, B430010N18Rik Protein, TIM-4 Protein, Tim4 Protein, SMUCKLER Protein, TIM4 Protein, T-cell immunoglobulin and mucin domain containing 4 Protein, T-cell immunoglobulin and mucin domain containing 4 L homeolog Protein, T cell immunoglobulin and mucin domain containing 4 Protein, Timd4 Protein, TIMD4 Protein, timd4.L Protein
- Background
- Tim4 is a transmembrane protein as the phosphatidylserine (PS) receptor, known as T cell immunoglobulin and mucin domain containing protein-4. It is expressed highly in macrophages, and macrophage Tim-4 inhibits inflammation under various conditions of immune activation.
- Molecular Weight
- 32.43 kDa. Due to glycosylation, the protein migrates to 78-98 kDa based on Tris-Bis PAGE result.
- Pathways
- Cancer Immune Checkpoints
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