GLP1R Protein (Biotin,His-Avi Tag)
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- Target See all GLP1R Proteins
- GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GLP1R protein is labelled with Biotin,His-Avi Tag.
- Purpose
- Biotinylated Human GLP1R Protein, His,Avitag™
- Sequence
- Ala 21 - Glu 139
- Characteristics
- Biotinylated Human GLP1R, His,Avitag is expressed from human 293 cells (HEK293). It contains AA Ala 21 - Glu 139 (Accession # P43220-1).
- Purity
- 90,00 %
- Endotoxin Level
- 1.0 EU per μg
- Top Product
- Discover our top product GLP1R Protein
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Glucagon-Like Peptide 1 Receptor (GLP1R) (AA 22-145) protein (His tag)
GLP1R Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Glucagon-Like Peptide 1 Receptor (GLP1R) (AA 24-145) protein (His tag)GLP1R Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
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- Comment
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This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 17.3 kDa. The protein migrates as 30-34 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
- Storage Comment
- -20°C
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- Target
- GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))
- Alternative Name
- GLP1R (GLP1R Products)
- Synonyms
- GLP1R Protein, LOC100228311 Protein, GLP-1R Protein, GLP1Rc Protein, Glip Protein, RATGL1RCP Protein, glucagon like peptide 1 receptor Protein, glucagon-like peptide 1 receptor Protein, GLP1R Protein, Glp1r Protein
- Background
- Synonyms:GLP-1, GLP-1-R, GLP-1R, glucagon like peptide 1 receptor,Description:This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke.
- Molecular Weight
- 17.3 kDa
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Hormone Transport, cAMP Metabolic Process, Feeding Behaviour
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