NPTX2 Protein (His tag)
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- Target See all NPTX2 Proteins
- NPTX2 (Neuronal Pentraxin II (NPTX2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NPTX2 protein is labelled with His tag.
- Purpose
- Human NPTX2 Protein, His Tag (MALS verified)
- Sequence
- Gly 16 - Leu 431
- Characteristics
- Human NPTX2, His Tag is expressed from human 293 cells (HEK293). It contains AA Gly 16 - Leu 431 (Accession # P47972).
- Purity
- 95,00 %
- Endotoxin Level
- 1.0 EU per μg
- Grade
- MALS verified
- Top Product
- Discover our top product NPTX2 Protein
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Neuronal Pentraxin II (NPTX2) (AA 1-431) protein (GST tag)
NPTX2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Neuronal Pentraxin II (NPTX2) protein (DYKDDDDK Tag)NPTX2 Origin: Human Host: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Neuronal Pentraxin II (NPTX2) protein (Myc-DYKDDDDK Tag)NPTX2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Comment
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This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 47.7 kDa. The protein migrates as 50-63 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
- Storage Comment
- -20°C
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- Target
- NPTX2 (Neuronal Pentraxin II (NPTX2))
- Alternative Name
- NPTX2 (NPTX2 Products)
- Synonyms
- NARP Protein, NP-II Protein, NP2 Protein, Narp Protein, np2 Protein, NPTX2 Protein, p50 Protein, nptx2 Protein, neuronal pentraxin 2 Protein, neuronal pentraxin II Protein, neuronal pentraxin 1 Protein, neuronal pentraxin 2a Protein, NPTX2 Protein, Nptx2 Protein, NPTX1 Protein, nptx2a Protein
- Background
- Synonyms:Neuronal pentraxin II,NP-II,Description:Neuronal Pentraxin 2 (NPTX2), also named neuronal activity-regulated pentraxin, is a secreted glycoprotein characterized by a cyclic multimeric structure. In vivo, NTPX2 exerts various neurological effects by combining with the transmembrane protein neuronal pen traxin receptor (NPTXR). NPTX2 was thought to play a vital role in transmitting neurotrans mitters and maintaining synaptic plasticity. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD.
- Molecular Weight
- 47.7 kDa
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