FGL2 Protein (AA 205-439) (Fc-DYKDDDDK Tag)

Catalog No. ABIN7454115

Product Details

Target: FGL2 (Fibrinogen-Like 2 (FGL2))

Protein Type: Recombinant

Protein Characteristics: AA 205-439

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This FGL2 protein is labelled with Fc-DYKDDDDK Tag.

Purpose: Human FGL2 Protein

Sequence: Val205-Pro439

Characteristics: Recombinant Human FGL2 Protein is expressed from HEK293 with hFc tag and Flag tag at the N-Terminus.It contains Val205-Pro439.

Purity: > 90 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human FGL2, hFc Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-FGL2 Antibody, hFc Tag with the EC50 of 34.3ng/ml determined by ELISA. See testing image for detail.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS, 200 mM Arginine ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: FGL2 (Fibrinogen-Like 2 (FGL2))

Alternative Name: FGL2 (FGL2 Products)

Synonyms: FGL2 Protein, wu:fj83c10 Protein, zgc:136619 Protein, si:ch211-276e22.3 Protein, fibroleukin Protein, T49 Protein, pT49 Protein, AI385601 Protein, musfiblp Protein, fibrinogen like 2 Protein, fibrinogen like 2 L homeolog Protein, fibrinogen-like 2a Protein, fibrinogen-like 2 Protein, fibrinogen-like protein 2 Protein, FGL2 Protein, fgl2.L Protein, fgl2a Protein, Fgl2 Protein

Background: Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immune responses. FGL2 is overexpressed in glioma, and its expression level is negatively associated with the prognosis of glioma patients.

Molecular Weight: 54.73 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.

UniProt: Q14314