GBA Protein (AA 40-536) (His tag)
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- Target See all GBA Proteins
- GBA (Glucosidase, Beta, Acid (GBA))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 40-536
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GBA protein is labelled with His tag.
- Purpose
- Human GBA/glucocerebrosidase Protein
- Sequence
- Ala40-Gln536
- Characteristics
- Recombinant Human GBA/glucocerebrosidase Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala40-Gln536.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
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Glucosidase, Beta, Acid (GBA) (AA 20-515) protein (His tag)Crystallography grade GBA Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Glucosidase, Beta, Acid (GBA) (Transcript Variant 1) (Active) protein (Myc-DYKDDDDK Tag)GBA Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD, Func, PI Active
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- GBA (Glucosidase, Beta, Acid (GBA))
- Alternative Name
- GBA (GBA Products)
- Synonyms
- GBA1 Protein, GCB Protein, GLUC Protein, BETA-GLUCOSIDASE Protein, T12J13.8 Protein, T12J13_8 Protein, beta glucosidase 25 Protein, PSPTO3318 Protein, PSPTO4290 Protein, GC Protein, GCase Protein, betaGC Protein, glucosylceramidase beta Protein, beta glucosidase 25 Protein, beta-glucosidase Protein, Beta-glucosidase Protein, glucosidase, beta, acid Protein, glucosylceramidase Protein, bglX-2 Protein, GBA Protein, BGLU25 Protein, PSPTO_3318 Protein, bglX Protein, bglA4 Protein, Gba Protein, LOC100399524 Protein, bglA.2 Protein, bglX-2 Protein
- Background
- Glucocerebrosidase (GBA) mutations are the most important genetic risk factor for the development of Parkinson disease (PD). GBA encodes the lysosomal enzyme glucocerebrosidase (GCase).
- Molecular Weight
- 56.69 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- NP_000148
- Pathways
- Cellular Glucan Metabolic Process
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