LILRA6 Protein (AA 41-474) (His tag)

Catalog No. ABIN7454167

Product Details

Target: LILRA6 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 6 (LILRA6))

Protein Type: Recombinant

Protein Characteristics: AA 41-474

Origin: Cynomolgus

Source: HEK-293 Cells

Purification tag / Conjugate: This LILRA6 protein is labelled with His tag.

Purpose: Cynomolgus LILRA6/CD85b/ILT8 Protein

Sequence: Gly41-His474

Characteristics: Recombinant Cynomolgus LILRA6/CD85b/ILT8 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly41-His474.

Purity: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: LILRA6 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 6 (LILRA6))

Alternative Name: LILRA6 (LILRA6 Products)

Synonyms: CD85b Protein, ILT-8 Protein, ILT5 Protein, ILT8 Protein, LILRB3 Protein, LILRB6 Protein, LIRe Protein, leukocyte immunoglobulin like receptor A6 Protein, leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 Protein, LILRA6 Protein

Background: The LILRs are a family of receptors that regulate the activities of myelomonocytic cells. Specific allelic variants of two related members of the LILR family, LILRB3 and LILRA6, interact with a ligand exposed on necrotic glandular epithelial cells. The extracellular domains of LILRB3 and LILRA6 are very similar and their genes are highly polymorphic.

Molecular Weight: 48.28 kDa. Due to glycosylation, the protein migrates to 68-75 kDa based on Tris-Bis PAGE result.

UniProt: A0A2K5VN04