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TPBG Protein (AA 32-361) (His tag)

TPBG Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7454221
  • Target See all TPBG Proteins
    TPBG (Trophoblast Glycoprotein (TPBG))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 32-361
    Origin
    • 17
    • 4
    • 3
    • 2
    • 1
    Mouse
    Source
    • 14
    • 4
    • 2
    • 2
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This TPBG protein is labelled with His tag.
    Purpose
    Mouse TPBG/5T4 Protein
    Sequence
    Ser32-Ser361
    Characteristics
    Recombinant Mouse TPBG/5T4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser32-Ser361.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product TPBG Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    TPBG (Trophoblast Glycoprotein (TPBG))
    Alternative Name
    TPBG (TPBG Products)
    Synonyms
    5T4 Protein, 5T4AG Protein, M6P1 Protein, AW495680 Protein, TPBG Protein, tpbg Protein, trophoblast glycoprotein Protein, trophoblast glycoprotein b Protein, TPBG Protein, Tpbg Protein, tpbgb Protein, tpbg Protein
    Background
    The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR4/CXCL12, Wnt, and Hippo pathways which may all contribute through the mobilization of CSCs.
    Molecular Weight
    36.86 kDa. Due to glycosylation, the protein migrates to 52-70 kDa based on Tris-Bis PAGE result.
    UniProt
    Q9Z0L0
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