TMIGD2 Protein (Fc Tag)

Catalog No. ABIN7490847

Product Details

Target: TMIGD2 (Transmembrane and Immunoglobulin Domain Containing 2 (TMIGD2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This TMIGD2 protein is labelled with Fc Tag.

Purpose: Recombinant human TMIGD2 protein with C-terminal human Fc tag

Specificity: TMIGD2 (Leu23-Gly150) hFc (Glu99-Ala330)

Characteristics: Extracellular Domain Protein

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: TMIGD2 (Transmembrane and Immunoglobulin Domain Containing 2 (TMIGD2))

Alternative Name: TMIGD2 (TMIGD2 Products)

Synonyms: IGPR-1 Protein, IGPR1 Protein, transmembrane and immunoglobulin domain containing 2 Protein, TMIGD2 Protein

Background: CD28 homolog, IGPR-1
Description: Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.[UniProtKB/Swiss-Prot Function]

Molecular Weight: predicted molecular mass of 40.1 kDa after removal of the signal peptide. The apparent molecular mass of TMIGD2-hFc is 55-70 kDa due to glycosylation.

UniProt: Q96BF3