ADAM15 Protein (Fc Tag)
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- Target See all ADAM15 Proteins
- ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ADAM15 protein is labelled with Fc Tag.
- Purpose
- Recombinant human ADAM15 protein with C-terminal human Fc tag
- Specificity
- ADAM15 (Leu18-Thr696) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product ADAM15 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))
- Alternative Name
- ADAM15 (ADAM15 Products)
- Synonyms
- ADAM15 Protein, mdc15 Protein, MDC15 Protein, metargidin Protein, tMDCVI Protein, ADAM metallopeptidase domain 15 Protein, ADAM metallopeptidase domain 15 L homeolog Protein, a disintegrin and metallopeptidase domain 15 (metargidin) Protein, ADAM15 Protein, adam15.L Protein, adam15 Protein, Adam15 Protein
- Background
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ADAM 15, MDC-15
Description: The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] - Molecular Weight
- predicted molecular mass of 100.0 kDa after removal of the signal peptide. The apparent molecular mass of ADAM15-hFc is 100-130 kDa due to glycosylation.
- UniProt
- Q13444
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