IL28A Protein (His tag)
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- Target See all IL28A Proteins
- IL28A (Interleukin 28A (Interferon, lambda 2) (IL28A))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL28A protein is labelled with His tag.
- Purpose
- Recombinant Human Interferon Lambda-2 is produced by our Mammalian expression system and the target gene encoding Val26-Val200 is expressed with a 6His tag at the C-terminus.
- Characteristics
- Extracellular Domain Protein
- Purity
- Greater than 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product IL28A Protein
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Interleukin 28A (Interferon, lambda 2) (IL28A) (Active) protein
IL28A Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 28A (Interferon, lambda 2) (IL28A) (AA 26-200) protein (His tag)Crystallography grade IL28A Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 28A (Interferon, lambda 2) (IL28A) (AA 20-193) protein (His tag)Crystallography grade IL28A Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 28A (Interferon, lambda 2) (IL28A) (AA 26-200) protein (His tag)IL28A Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- a 0.2 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C
- Storage Comment
- Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- IL28A (Interleukin 28A (Interferon, lambda 2) (IL28A))
- Alternative Name
- IL-28A (IL28A Products)
- Synonyms
- EG330496 Protein, IL-28A Protein, Il28a Protein, IL28A Protein, interferon lambda 2 Protein, Ifnl2 Protein, IFNL2 Protein
- Background
- Interferon lambda-2, IFN-lambda-2, Cytokine Zcyto20, Interleukin-28A, IL-28A, IFNL2, IL28A, ZCYTO20IL-28A (Interferon-λ2, IFN-λ2), IL-28B/IFN-λ3, and IL-29/IFN-λ1 are type III interferons which are distantly related to IL-10 family and type I IFN family cytokines. Mature human IL-28A is an approximately 22-25 kDa protein that shares 66 % amino acid (aa) sequence identity with mouse and rat IL-28A and shows cross-species activity. It shares 96 % and 70 % aa sequence identity with human IL-28B and IL-29, respectively. IL-28A promotes the Th1 polarization of dendritic cells in the airway and inhibits Th2 and Th17 mediated inflammation. IL-28A additionally exhibits anti-tumor activity, in part by enhancing IL-12 dependent anti-tumor CTL responses in vivo. In contrast, it is up-regulated in invasive bladder cancer where it promotes tumor cell migration.
- Molecular Weight
- 20.6 KDa
- UniProt
- Q8IZJ0
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