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IL28A Protein (His tag)

IL28A Origin: Human Host: HEK-293 Cells Recombinant > 97 % by SDS-PAGE.
Catalog No. ABIN7534305
  • Target See all IL28A Proteins
    IL28A (Interleukin 28A (Interferon, lambda 2) (IL28A))
    Protein Type
    Recombinant
    Origin
    • 7
    • 3
    Human
    Source
    • 6
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IL28A protein is labelled with His tag.
    Purpose
    Recombinant Human IFN-lambda 2/IL-28A Protein
    Sequence
    VPVARLHGAL PDARGCHIAQ FKSLSPQELQ AFKRAKDALE ESLLLKDCRC HSRLFPRTWD LRQLQVRERP MALEAELALT LKVLEATADT DPALVDVLDQ PLHTLHHILS QFRACIQPQP TAGPRTRGRL HHWLYRLQEA PKKESPGCLE ASVTFNLFRL LTRDLNCVAS GDLCV
    Specificity
    Val26-Val200
    Purity
    > 97 % by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    < 0.1 EU/μg of the protein by LAL method.
    Top Product
    Discover our top product IL28A Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    Buffer
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • Target
    IL28A (Interleukin 28A (Interferon, lambda 2) (IL28A))
    Alternative Name
    IFN-lambda 2/IL-28A (IL28A Products)
    Synonyms
    EG330496 Protein, IL-28A Protein, Il28a Protein, IL28A Protein, interferon lambda 2 Protein, Ifnl2 Protein, IFNL2 Protein
    Background

    Description: IL 28A (Interferon-lambda 2, IFN-lambda 2), IL-28B/IFN-lambda 3, and IL-29/IFN-lambda 1 are type III interferons which are distantly related to IL-10 family and type I IFN family cytokines . IL 28A ,interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine which are expression can be induced by viral infection.In the liver, the IL-28A induced Th1 cytokine response contributes to inflammation in T cell mediated hepatitis. IL-28A additionally exhibits anti-tumor activity, in part by enhancing IL-12 dependent anti-tumor CTL responses in vivo . In contrast, it is up-regulated in invasive bladder cancer where it promotes tumor cell migration.

    Name: IFNL2,IL-28A,IL28A, IFNL2a, IFNL3a, IL-28A

    Gene ID
    282616
    UniProt
    Q8IZJ0
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