LY6H Protein (Fc Tag)

Catalog No. ABIN7491421

Product Details

Target: LY6H (Lymphocyte Antigen 6 Complex, Locus H (LY6H))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This LY6H protein is labelled with Fc Tag.

Purpose: Recombinant Human LY6H Protein with C-terminal human Fc tag

Specificity: LY6H (Leu26-Gly115) hFc (Glu99-Ala330)

Characteristics: Extracellular Domain Protein

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: LY6H (Lymphocyte Antigen 6 Complex, Locus H (LY6H))

Alternative Name: LY6H (LY6H Products)

Synonyms: LY6H Protein, NMLY6 Protein, lymphocyte antigen 6 family member H Protein, lymphocyte antigen 6 complex, locus H Protein, Ly6h Protein, LY6H Protein

Background: NMLY6Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4-containing nAChRs maximum response. May play a role in the intracellular trafficking of alpha-7-containing nAChRs and may inhibit their expression at the cell surface. Seems to inhibit alpha-7/CHRNA7 signaling in hippocampal neurons.[UniProtKB/Swiss-Prot Function]

Molecular Weight: predicted molecular mass of 36.0 kDa after removal of the signal peptide. The apparent molecular mass of LY6H-hFc is 35-55 kDa due to glycosylation.

UniProt: O94772