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GIPR Protein (Fc Tag)

GIPR Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7491455
  • Target See all GIPR Proteins
    GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))
    Protein Type
    Recombinant
    Origin
    • 3
    • 2
    Human
    Source
    • 4
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This GIPR protein is labelled with Fc Tag.
    Purpose
    Recombinant Human GIPR Protein with C-terminal human Fc tag
    Specificity
    GIPR (Arg22-Gln138) hFc (Glu99-Ala330)
    Characteristics
    Extracellular Domain Protein
    Purity
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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    Discover our top product GIPR Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))
    Alternative Name
    GIPR (GIPR Products)
    Synonyms
    GIPR Protein, PGQTL2 Protein, GIP-R Protein, Gm1081 Protein, Gm160 Protein, Gippr Protein, RATGIPPR Protein, gastric inhibitory polypeptide receptor Protein, glucagon receptor Protein, GIPR Protein, LOC100303705 Protein, Gipr Protein
    Background
    PGQTL2
    Description: This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. [provided by RefSeq, Oct 2011]
    Molecular Weight
    predicted molecular mass of 39.6 kDa after removal of the signal peptide. The apparent molecular mass of GIPR-hFc is 35-55 kDa due to glycosylation.
    UniProt
    P48546
    Pathways
    Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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