Muscarinic Acetylcholine Receptor M2 Protein (Fc Tag)
CHRM2
Origin: Human
Host: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- Target See all Muscarinic Acetylcholine Receptor M2 (CHRM2) Proteins
- Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Muscarinic Acetylcholine Receptor M2 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human CHRM2 Protein with C-terminal human Fc tag
- Specificity
- CHRM2 (Met1-Glu22) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product CHRM2 Protein
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Cholinergic Receptor, Muscarinic 2 (CHRM2) (AA 251-350) protein (GST tag)
CHRM2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))
- Alternative Name
- CHRM2 (CHRM2 Products)
- Synonyms
- HM2 Protein, AChR-M2 Protein, Chrm-2 Protein, M2 Protein, chrm2 Protein, Acm2 Protein, GPM2 Protein, cholinergic receptor muscarinic 2 Protein, cholinergic receptor, muscarinic 2, cardiac Protein, cholinergic receptor, muscarinic 2a Protein, cholinergic receptor, muscarinic 2 Protein, CHRM2 Protein, Chrm2 Protein, chrm2a Protein
- Background
- HM2The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]
- Molecular Weight
- predicted molecular mass of 28.6 kDa after removal of the signal peptide. The apparent molecular mass of CHRM2-hFc is 35-55 kDa due to glycosylation.
- UniProt
- P08172
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