ESYT1 Protein
ESYT1
Origin: Human
Host: HEK-293 Cells
Synthetic
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- Target See all ESYT1 products
- ESYT1 (Extended Synaptotagmin-Like Protein 1 (ESYT1))
- Protein Type
- Synthetic
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human ESYT1 full length protein-synthetic nanodisc
- Characteristics
- Full Length Transmembrane Proteins (synthetic Nanodisc)
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Extended Synaptotagmin-Like Protein 1 (ESYT1) protein (Myc-DYKDDDDK Tag)
ESYT1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- Comment
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- ESYT1 (Extended Synaptotagmin-Like Protein 1 (ESYT1))
- Alternative Name
- ESYT1 (ESYT1 Products)
- Synonyms
- FAM62A Protein, fam62a Protein, si:ch211-239j9.4 Protein, DKFZp459I1628 Protein, MBC2 Protein, Fam62a Protein, Mbc2 Protein, vp115 Protein, extended synaptotagmin 1 Protein, extended synaptotagmin-like protein 1b Protein, extended synaptotagmin-like protein 1 Protein, ESYT1 Protein, esyt1b Protein, Esyt1 Protein
- Background
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FAM62A, MBC2
Description: Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport (By similarity). Binds calcium (via the C2 domains) and translocates to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels. Helps tether the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane.[UniProtKB/Swiss-Prot Function] - Molecular Weight
- The human full length ESYT1 protein has a MW of 122.9 kDa
- UniProt
- Q9BSJ8
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