MLC1 Protein
Origin: Human
Host: HEK-293 Cells
Synthetic
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- Target See all MLC1 products
- MLC1
- Protein Type
- Synthetic
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human MLC1 full length protein-synthetic nanodisc
- Characteristics
- Full Length Transmembrane Proteins (synthetic Nanodisc)
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- Application Notes
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- Comment
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- MLC1
- Abstract
- MLC1 Products
- Synonyms
- LVM Protein, MLC Protein, VL Protein, AW048630 Protein, BB074274 Protein, Kiaa0027-hp Protein, WKL1 Protein, mKIAA0027 Protein, si:ch211-192n14.1 Protein, megalencephalic leukoencephalopathy with subcortical cysts 1 Protein, megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human) Protein, MLC1 Protein, Mlc1 Protein, mlc1 Protein
- Background
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LVM, MLC, VL
Description: The function of this gene product is unknown, however, homology to other proteins suggests that it may be an integral membrane transporter. Mutations in this gene have been associated with megalencephalic leukoencephalopathy with subcortical cysts, an autosomal recessive neurological disorder. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] - Molecular Weight
- The human full length MLC1 protein has a MW of 41.2 kDa
- UniProt
- Q15049
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