IL31RA Protein (Fc Tag)
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- Target See all IL31RA Proteins
- IL31RA (Interleukin 31 Receptor A (IL31RA))
- Protein Type
- Recombinant
- Origin
- Cynomolgus, Rhesus Monkey
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL31RA protein is labelled with Fc Tag.
- Purpose
- Cynomolgus/Rhesus macaque IL-31 RA Protein, Fc Tag
- Sequence
- Ala 20 - Glu 519
- Characteristics
- Cynomolgus/Rhesus macaque IL-31 RA Protein, Fc Tag (ILA-H525b) is expressed from human 293 cells (HEK293). It contains AA Ala 20 - Glu 519 (Accession # XP_005556977.2).
- Purity
- 90 %
- Endotoxin Level
- 1.0 EU per μg
- Top Product
- Discover our top product IL31RA Protein
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- Comment
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This protein carries a human IgG1 Fc tag at the C-terminus. (Fc) The protein has a calculated MW of 84.5 kDa. The protein migrates as 110-140 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
- Storage Comment
- -20°C
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- Target
- IL31RA (Interleukin 31 Receptor A (IL31RA))
- Alternative Name
- IL-31 RA (IL31RA Products)
- Synonyms
- IL31RA Protein, CRL Protein, CRL3 Protein, GLM-R Protein, GLMR Protein, GPL Protein, IL-31RA Protein, PLCA2 Protein, PRO21384 Protein, hGLM-R Protein, Glmr Protein, NR10 Protein, interleukin 31 receptor A Protein, IL31RA Protein, Il31ra Protein
- Background
- Interleukin-31 receptor subunit alpha is a protein that in humans is encoded by the IL31RA gene, also known as IL-31 receptor subunit alpha, IL-31RA, GLM-R, Gp130-like receptor, CRL3, GPL. Oncostatin M receptor (OSMR) and IL31RA form the heterodimeric receptor through which IL31 signals. IL31RA is a strong activator of STAT3 and STAT5, whereas STAT1 is only marginally tyrosine-phosphorylated. dditionally, demonstrate Jak1 binding to GPL and its activation in heteromeric complexes with the OSMRbeta but also in a homomeric receptor complex.
- Molecular Weight
- 84.5 kDa
- NCBI Accession
- XP_005556977
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