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Claudin 4 Protein (CLDN4) (His tag,Twin-Strep tag)

CLDN4 Origin: Human Host: Insect Cells Recombinant 90 %
Catalog No. ABIN7489008
  • Target See all Claudin 4 (CLDN4) Proteins
    Claudin 4 (CLDN4)
    Protein Type
    Recombinant
    Origin
    • 9
    • 2
    • 1
    Human
    Source
    • 5
    • 2
    • 2
    • 2
    Insect Cells
    Purification tag / Conjugate
    This Claudin 4 protein is labelled with His tag,Twin-Strep tag.
    Purpose
    Human Claudin-4 Protein, His,Twin-Strep Tag (Detergent)
    Sequence
    Met 1 - Val 209
    Characteristics
    Human Claudin-4 Protein, His,Twin-Strep Tag is expressed from Baculovirus-Insect cells. It contains AA Met 1 - Val 209 (Accession # O14493-1).
    Purity
    90 %
    Endotoxin Level
    1.0 EU per μg
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    Discover our top product CLDN4 Protein
  • Comment

    This protein carries a polyhistidine tag at the N-terminus and a twin strep tag at the C-terminus. (10xHis , Twin-Strep) The protein has a calculated MW of 27.5 kDa. The protein migrates as 23-24 kDa under reducing (R) condition (SDS-PAGE).

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    50 mM Tris, 150 mM NaCl, DDM, CHS, pH 7.5
    Storage
    -80 °C
    Storage Comment
    -70°C
  • Target
    Claudin 4 (CLDN4)
    Alternative Name
    Claudin-4 (CLDN4 Products)
    Synonyms
    CPE-R Protein, CPER Protein, CPETR Protein, CPETR1 Protein, WBSCR8 Protein, hCPE-R Protein, Cep-r Protein, Cpetr Protein, Cpetr1 Protein, CLDN4 Protein, cper Protein, cpe-r Protein, cpetr Protein, cpetr1 Protein, hcpe-r Protein, wbscr8 Protein, claudin 4 Protein, claudin 4 L homeolog Protein, CLDN4 Protein, Cldn4 Protein, cldn4 Protein, cldn4.L Protein
    Background
    The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.
    Molecular Weight
    27.5 kDa
    Pathways
    Hepatitis C
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