Glucagon Receptor Protein-VLP (GCGR)
Quick Overview for Glucagon Receptor Protein-VLP (GCGR) (ABIN7489074)
Target
See all Glucagon Receptor (GCGR) ProteinsProtein Type
Origin
Source
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Purpose
- Human GCGR / Glucagon receptor Full Length Protein (VLP)
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Sequence
- Ala 26 - Asn 432
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Characteristics
- Human GCGR Full Length Protein (VLP) is expressed from human 293 cells (HEK293). It contains AA Ala 26 - Asn 432 (Accession # P47871-1).
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Endotoxin Level
- 1.0 EU per μg
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Glucagon Receptor (GCGR) protein
GCGR Origin: Human Host: HEK-293 Cells Synthetic Nanodisc
Glucagon Receptor (GCGR) (AA 26-136) protein (Fc Tag)GCGR Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Glucagon Receptor (GCGR) (AA 26-136) protein (His tag)GCGR Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, Arginine, pH 7.4
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Storage
- -80 °C
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Storage Comment
- -70°C
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- Glucagon Receptor (GCGR)
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Alternative Name
- GCGR
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Background
- The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of type 2 diabetes mellitus (T2DM) . The ever increasing prevalence of type 2 diabetes mellitus in the developed and developing nations calls for the introduction of new and more effective treatments. Glucagon receptor (GCGR) antagonists are highly validated in preclinical models of T2DM and thus have the potential to be developed as a new therapy.
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Pathways
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
Target
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