Glucagon Receptor Protein (GCGR) (AA 26-136) (His tag)
GCGR
Origin: Human
Host: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
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- Target See all Glucagon Receptor (GCGR) Proteins
- Glucagon Receptor (GCGR)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 26-136
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Glucagon Receptor protein is labelled with His tag.
- Characteristics
- Human GCGR / Glucagon receptor Protein, His Tag (MALS verified)
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 0.1 EU per μg by the LAL method.
- Top Product
- Discover our top product GCGR Protein
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- Application Notes
- MALS verified
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
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- Target
- Glucagon Receptor (GCGR)
- Alternative Name
- GCGR (GCGR Products)
- Synonyms
- GCGR Protein, GGR Protein, GR Protein, glucagon receptor Protein, GCGR Protein, Gcgr Protein
- Background
- G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.
- Molecular Weight
- 14.9 kDa
- Pathways
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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