Glucagon Receptor Protein (GCGR)

Catalog No. ABIN7491649

Product Details

Target: Glucagon Receptor (GCGR)

Protein Type: Synthetic

Origin: Human

Source: HEK-293 Cells

Purpose: Human GCGR full length protein-synthetic nanodisc

Characteristics: Full Length Transmembrane Proteins (synthetic Nanodisc)

Application Details

Application Notes:

• Applications for VLPs:
• ELISA
• SPR affinity analysis
• Phage display screening
• Immunization
• Cell based assays
• CAR-T cell screening
• Protein cystal structure analysis

Comment:

Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: Glucagon Receptor (GCGR)

Alternative Name: GCGR (GCGR Products)

Synonyms: GCGR Protein, GGR Protein, GR Protein, glucagon receptor Protein, GCGR Protein, Gcgr Protein

Background: GGR, GL-R, MVAH
Description: The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).[provided by RefSeq, Jan 2010]

Molecular Weight: The human full length GCGR protein has a MW of 54.01 kDa

UniProt: P47871

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process