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KLKB1 Protein (His tag)

MALS verified KLKB1 Origin: Human Host: HEK-293 Cells Recombinant 95 % Active
Catalog No. ABIN7488777
  • Target See all KLKB1 Proteins
    KLKB1 (Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 4
    • 3
    • 3
    • 1
    • 1
    Human
    Source
    • 4
    • 4
    • 3
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This KLKB1 protein is labelled with His tag.
    Purpose
    Human Plasma Kallikrein / KLKB1 Protein, His Tag (active enzyme, MALS verified)
    Sequence
    Gly 20 - Ala 638
    Characteristics
    Human Plasma Kallikrein/KLKB1, His Tag is expressed from human 293 cells (HEK293). It contains AA Gly 20 - Ala 638 (Accession # P03952-1).
    Purity
    95 %
    Endotoxin Level
    1.0 EU per μg
    Grade
    MALS verified
    Top Product
    Discover our top product KLKB1 Protein
  • Comment

    This protein carries a polyhistidine tag at the C-terminus. (10xHis) The protein has a calculated MW of 71.1 kDa. The protein migrates as 70-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    50 mM Tris 150 mM NaCl,PH7.5
    Storage
    -80 °C
    Storage Comment
    -70°C
  • Target
    KLKB1 (Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1))
    Alternative Name
    Plasma Kallikrein (KLKB1 Products)
    Synonyms
    KLK3 Protein, PPK Protein, APS Protein, Kal-3 Protein, Kal3 Protein, Klk3 Protein, PSA Protein, KALP15 Protein, Kalp1 Protein, KLKB1 Protein, DKFZp459J2015 Protein, klkb1 Protein, kallikrein B1 Protein, kallikrein B, plasma 1 Protein, plasma kallikrein Protein, Plasma kallikrein Protein, kallikrein B, plasma (Fletcher factor) 1 Protein, coagulation factor XI Protein, kallikrein B1 L homeolog Protein, KLKB1 Protein, Klkb1 Protein, CpipJ_CPIJ004042 Protein, CpipJ_CPIJ014955 Protein, CpipJ_CPIJ020108 Protein, VAA_02266 Protein, LOC100549617 Protein, klkb1 Protein, klkb1.L Protein
    Background
    Human Plasma Kallikrein, a serine protease, is synthesized in the liver and circulates in the plasma by binding to high molecular weight (HMW) kininogen or as a free zymogen. The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.
    Molecular Weight
    71.1 kDa
    Pathways
    Complement System, Brown Fat Cell Differentiation
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