Adenylosuccinate Lyase Protein (ADSL) (AA 2-484) (His tag)

Catalog No. ABIN7504226

Product Details

Target: Adenylosuccinate Lyase (ADSL)

Protein Type: Recombinant

Protein Characteristics: AA 2-484

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This Adenylosuccinate Lyase protein is labelled with His tag.

Purpose: Human Adenylosuccinate Lyase Protein

Sequence: Ala2-Leu484

Characteristics: Recombinant Human Adenylosuccinate Lyase Protein is expressed from E.coli with His tag at the N-Terminus.It contains Ala2-Leu484.

Purity: > 95 % as determined by Tris-Bis PAGE

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Adenylosuccinate Lyase (ADSL)

Alternative Name: Adenylosuccinate Lyase (ADSL Products)

Synonyms: fi60b04 Protein, zgc:56061 Protein, wu:fi60b04 Protein, MGC53383 Protein, MGC69239 Protein, adsL Protein, F15C21.8 Protein, F15C21_8 Protein, AMPS Protein, ASASE Protein, ASL Protein, Adl Protein, Asl Protein, purB Protein, adenylosuccinate lyase Protein, adenylosuccinate lyase L homeolog Protein, adenylosuccinase; ASL Protein, Adenylosuccinate lyase Protein, L-Aspartase-like family protein Protein, ADSL Protein, adsl Protein, adsl.L Protein, ASL Protein, purB Protein, purB,adsL Protein, Mrub_2293 Protein, MMAH_RS02975 Protein, Arnit_0089 Protein, Mesil_1058 Protein, Slip_0597 Protein, Trad_2452 Protein, Deba_0652 Protein, Toce_1174 Protein, Acear_2324 Protein, Igag_0272 Protein, Saut_2156 Protein, Fbal_1996 Protein, Ndas_2434 Protein, Ilyop_0196 Protein, Lbys_2961 Protein, MFER_RS02920 Protein, Palpr_2192 Protein, Calni_0061 Protein, Ftrac_3746 Protein, AT1G36280 Protein, Olsu_1764 Protein, Adsl Protein

Background: Adenylosuccinate lyase (ADSL) is an essential enzyme for de novo purine biosynthesis, ADSL functions in de novo purine synthesis (DNPS) and the purine nucleotide cycle. Adenylosuccinate lyase ADSL) deficiency is a defect of purine metabolism affecting purinosome assembly and reducing metabolite fluxes through purine de novo synthesis and purine nucleotide recycling pathways.

Molecular Weight: 56.28 kDa same as Tris-Bis PAGE result.

Pathways: Ribonucleoside Biosynthetic Process