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HHLA2 Protein (AA 21-345) (His tag)

HHLA2 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7504236
  • Target See all HHLA2 Proteins
    HHLA2 (HERV-H LTR-Associating 2 (HHLA2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 21-345
    Origin
    • 8
    • 1
    Cynomolgus
    Source
    • 7
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This HHLA2 protein is labelled with His tag.
    Purpose
    Cynomolgus B7-H7/HHLA2 Protein
    Sequence
    Ile21-Asn345
    Characteristics
    Recombinant Cynomolgus B7-H7/HHLA2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ile21-Asn345.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
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    Discover our top product HHLA2 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    HHLA2 (HERV-H LTR-Associating 2 (HHLA2))
    Alternative Name
    B7-H7 (HHLA2 Products)
    Synonyms
    B7H7 Protein, HERV-H LTR-associating 2 Protein, HHLA2 Protein, hhla2 Protein
    Background
    B7-H7, also known as HHLA2 (HERV-H LTR-associating 2), is a member of the B7 family of immune regulatory proteins.Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
    Molecular Weight
    38.31 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
    NCBI Accession
    XP_005548285
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