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CEACAM7 Protein (AA 36-242) (His tag)

CEACAM7 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7504297
  • Target See all CEACAM7 products
    CEACAM7 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 7 (CEACAM7))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 36-242
    Origin
    Human
    Source
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CEACAM7 protein is labelled with His tag.
    Purpose
    Human CEACAM-7 Protein
    Sequence
    Thr36-Ser242
    Characteristics
    Recombinant Human CEACAM-7 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Thr36-Ser242.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CEACAM7 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 7 (CEACAM7))
    Alternative Name
    CEACAM-7 (CEACAM7 Products)
    Synonyms
    CEACAM7 Protein, CEA Protein, CGM2 Protein, carcinoembryonic antigen related cell adhesion molecule 7 Protein, carcinoembryonic antigen-related cell adhesion molecule 6 Protein, CEACAM7 Protein, LOC612471 Protein
    Background
    Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to a group of mammalian immunoglobulin-related glycoproteins. They are involved in cell-cell recognition and modulate cellular processes that range from the shaping of tissue architecture and neovascularization to the regulation of insulin homeostasis and T-cell proliferation. CEACAM7 (CGM2), a member of the CEA family of proteins with expression restricted to the colon and pancreas, as a potential CAR T-cell target for PDAC.
    Molecular Weight
    24.45 kDa. Due to glycosylation, the protein migrates to 45-65 kDa based on Tris-Bis PAGE result.
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