CD130/gp130 Protein (AA 23-619) (His tag)
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- Target See all CD130/gp130 (IL6ST) Proteins
- CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-619
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD130/gp130 protein is labelled with His tag.
- Purpose
- Human gp130/CD130/IL-6 R beta Protein
- Sequence
- Glu23-Glu619
- Characteristics
- Recombinant Human gp130/CD130/IL-6 R beta Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu23-Glu619.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product IL6ST Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
- Alternative Name
- gp130 (IL6ST Products)
- Synonyms
- CD130 Protein, CDW130 Protein, GP130 Protein, IL-6RB Protein, 5133400A03Rik Protein, AA389424 Protein, BB405851 Protein, D13Ertd699e Protein, gp130 Protein, Ac1055 Protein, Gp130 Protein, Il-6rb Protein, IL-6 Protein, interleukin 6 signal transducer Protein, IL6ST Protein, Il6st Protein, il6st Protein
- Background
- Gp130 is a common signal transducing component of the functional receptor complexes for the interleukin (IL)-6 family of cytokines, ie, IL-6, IL-11, leukemia inhibitory factor (LIF), oncostatin M, ciliary neurotrophic factor, and cardiotrophin-1. These cytokines exhibit pleiotropic biological activities in, for instance, immune, hematopoietic, and neural systems, and function in a redundant manner owing to the shared usage of gp130.
- Molecular Weight
- 68.94 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Tris-Bis PAGE result.
- Pathways
- JAK-STAT Signaling, Cellular Glucan Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Cancer Immune Checkpoints
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