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SPINT1 Protein (AA 36-433) (His tag)

SPINT1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7504349
  • Target See all SPINT1 Proteins
    SPINT1 (serine Peptidase Inhibitor, Kunitz Type 1 (SPINT1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 36-433
    Origin
    • 7
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This SPINT1 protein is labelled with His tag.
    Purpose
    Human HAI-1 Protein
    Sequence
    Gly36-Val433
    Characteristics
    Recombinant Human HAI-1 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gly36-Val433.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product SPINT1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    SPINT1 (serine Peptidase Inhibitor, Kunitz Type 1 (SPINT1))
    Alternative Name
    HAI-1 (SPINT1 Products)
    Synonyms
    HAI-1 Protein, HAI Protein, HAI1 Protein, MANSC2 Protein, cb376 Protein, sb:cb376 Protein, spint1l Protein, zgc:64075 Protein, serine peptidase inhibitor, Kunitz type 1 Protein, serine protease inhibitor, Kunitz type 1 Protein, serine peptidase inhibitor, Kunitz type 1 b Protein, serine peptidase inhibitor, Kunitz type 1 a Protein, SPINT1 Protein, Spint1 Protein, spint1b Protein, spint1a Protein
    Background
    SPINT1, also known as HAI-1, is a Kunitz-type serine protease inhibitor that inhibits multiple proteases including hepatocyte growth factor (HGF) activator and matriptase. SPINT1 has been shown to modulate HGF/MET activation in certain cancer types.
    Molecular Weight
    45.50 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.
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