PKC iota Protein (AA 10-596) (His tag)
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- Target See all PKC iota (PRKCI) Proteins
- PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 10-596
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This PKC iota protein is labelled with His tag.
- Purpose
- Human PKC iota Protein
- Sequence
- Met10-Val596
- Characteristics
- Recombinant Human PKC iota Protein is expressed from Baculovirus-Insect Cells with His tag at the C-terminus.It contains Met10-Val596.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product PRKCI Protein
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Protein Kinase C, iota (PRKCI) (AA 1-587) protein (GST tag)
PRKCI Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA, KAA
Protein Kinase C, iota (PRKCI) (AA 1-587) (Active) protein (His-GST)PRKCI Origin: Human Host: Insect cells (Sf9) Recombinant SDS, Func Active
Protein Kinase C, iota (PRKCI) (AA 1-100) protein (GST tag)PRKCI Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Protein Kinase C, iota (PRKCI) (AA 2-596) protein (His tag)Crystallography grade PRKCI Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Protein Kinase C, iota (PRKCI) (AA 2-595) protein (His tag)Crystallography grade PRKCI Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Protein Kinase C, iota (PRKCI) protein (Myc-DYKDDDDK Tag)PRKCI Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22 μm filtered solution in 50 mM Tris, 100 mM NaCl, 0.5 mM GSH, 0.5 mM PMSF, 10 % glycerol ( pH 7.4).
- Preservative
- PMSF
- Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))
- Alternative Name
- PKC iota (PRKCI Products)
- Synonyms
- DXS1179E Protein, PKCI Protein, nPKC-iota Protein, aPKC[l] Protein, hal Protein, has Protein, PRKCI Protein, PKC Protein, 2310021H13Rik Protein, AI427505 Protein, PKClambda Protein, Pkci Protein, Pkcl Protein, Prkcl Protein, aPKClambda Protein, mKIAA4165 Protein, protein kinase C iota Protein, protein kinase C, iota Protein, PRKCI Protein, prkci Protein, Prkci Protein
- Background
- PKClambda/iota belongs to the third group of the PKC family, atypical PKC (aPKC), together with PKCzeta based on its sequence divergence from conventional and novel PKCs observed not only in the N-terminal regulatory domain but also in the kinase domain. Although one of the most distinct features of aPKC is its single, unrepeated cysteine-rich domain, recent studies have revealed that the N-terminal regulatory domain has additional aPKC-specific structural motifs involved in various protein-protein interactions, which are important for the regulation and the subcellular targeting of aPKC.
- Molecular Weight
- 68.78 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.
- UniProt
- P41743
- Pathways
- Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, Tube Formation
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