Tropomyosin Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)
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- Target See all Tropomyosin (TPM1) Proteins
- Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 3
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Tropomyosin protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Tropomyosin-1 (TPM1) (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product TPM1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
- Alternative Name
- Tropomyosin-1 (Tpm1) (TPM1 Products)
- Synonyms
- alpha-fTM Protein, Tm7 Protein, tpm1 Protein, MGC84844 Protein, AA986836 Protein, AI854628 Protein, TM2 Protein, Tm3 Protein, Tmpa Protein, Tpm-1 Protein, alpha-TM Protein, Alpha-tm Protein, Tma2 Protein, Tmsa Protein, TPM1 Protein, fb37a09 Protein, tm Protein, wu:fb37a09 Protein, CH1 Protein, alpha-tm Protein, alpha-tropomyosin Protein, C15orf13 Protein, CMD1Y Protein, CMH3 Protein, HTM-alpha Protein, TMSA Protein, TPMA Protein, Tm1 Protein, zgc:171719 Protein, zgc:55951 Protein, zgc:77009 Protein, tropomyosin 1 (alpha) Protein, tropomyosin Protein, tropomyosin 1 Protein, tropomyosin 1, alpha Protein, alpha-tropomyosin Protein, tropomyosin 1 L homeolog Protein, TPM1 Protein, tm7 Protein, Tpm1 Protein, tpma Protein, tpm1.L Protein, Smp_044010.2 Protein, LOC732984 Protein, tpm1 Protein
- Background
- This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.
- Molecular Weight
- 32.6 kDa
- NCBI Accession
- NP_001018004
- Pathways
- Regulation of Actin Filament Polymerization
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