BMPR2 Protein (AA 27-150) (His tag)
-
- Target See all BMPR2 Proteins
- BMPR2 (Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 27-150
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BMPR2 protein is labelled with His tag.
- Sequence
- Ser27-Thr150
- Characteristics
- A DNA sequence encoding theHuman BMPR2 protein (Q13873) (Ser27-Thr150) was expressed with a N-His.
- Purity
- >85 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product BMPR2 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
-
- Target
- BMPR2 (Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))
- Alternative Name
- BMPR2 (BMPR2 Products)
- Synonyms
- BMPR-II Protein, BMPR3 Protein, BMR2 Protein, BRK-3 Protein, PPH1 Protein, T-ALK Protein, 2610024H22Rik Protein, AL117858 Protein, AW546137 Protein, BB189135 Protein, BMP-2 Protein, BMPR-2 Protein, BMPRII Protein, Gm20272 Protein, Bmpr-II Protein, bmprii Protein, bone morphogenetic protein receptor type 2 Protein, bone morphogenetic protein receptor, type II b (serine/threonine kinase) Protein, bone morphogenetic protein receptor, type II (serine/threonine kinase) Protein, BMPR2 Protein, bmpr2b Protein, Bmpr2 Protein
- Background
-
Background: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.
Synonym: BMP type-2 receptor,BMPR-2,Bone morphogenetic protein receptor type II,BMP type II receptor,BMPR-II
- Molecular Weight
- 26 kDa
- UniProt
- Q13873
- Pathways
- Growth Factor Binding
-