RAC3 Protein (AA 1-189) (His tag)

Catalog No. ABIN7505248

Product Details

Target: RAC3 (Ras-Related C3 Botulinum Toxin Substrate 3 (Rho Family, Small GTP Binding Protein Rac3) (RAC3))

Protein Type: Recombinant

Protein Characteristics: AA 1-189

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This RAC3 protein is labelled with His tag.

Sequence: Met 1-Cys 189

Characteristics: A DNA sequence encoding the Human Rac3 protein (P60763) (Met 1-Cys 189) was expressed with a N-His and C-His tag.

Purity: >95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: RAC3 (Ras-Related C3 Botulinum Toxin Substrate 3 (Rho Family, Small GTP Binding Protein Rac3) (RAC3))

Alternative Name: Rac3 (RAC3 Products)

Synonyms: Rac1B Protein, rac3 Protein, zgc:100831 Protein, Rac family small GTPase 3 Protein, RAS-related C3 botulinum substrate 3 Protein, Rac family small GTPase 3a Protein, RAC3 Protein, Rac3 Protein, rac3a Protein

Background:

Background: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of actin-based protusions including lamellipodia and membrane ruffles. Promotes cell adhesion and spreading on fibrinogen in a CIB1 and alpha-IIb/beta3 integrin-mediated manner.

Synonym: Ras-related C3 botulinum toxin substrate 3, RAC3,p21-Rac3,

Molecular Weight: 20.68 kDa

UniProt: P60763

Pathways: RTK Signaling, VEGF Signaling