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Caspase 8 Protein (CASP8) (AA 219-376) (His tag)

CASP8 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505388
  • Target See all Caspase 8 (CASP8) Proteins
    Caspase 8 (CASP8)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 219-376
    Origin
    • 7
    • 3
    • 2
    • 1
    Mouse
    Source
    • 11
    • 2
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This Caspase 8 protein is labelled with His tag.
    Sequence
    Ser 219-Gly 376
    Characteristics
    A DNA sequence encoding the Mouse CASP8 protein (O89110) (Ser219-Gly376) was expressed with a N-His .
    Purity
    >95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product CASP8 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    Caspase 8 (CASP8)
    Alternative Name
    Caspase-8 (CASP8 Products)
    Synonyms
    casp8-A Protein, xCaspase-8 Protein, casp8 Protein, CASP8 Protein, CASP-8 Protein, FLICE Protein, MACH Protein, Mch5 Protein, ALPS2B Protein, CAP4 Protein, Casp-8 Protein, MCH5 Protein, caspase-8 Protein, zgc:92075 Protein, caspase 8 L homeolog Protein, death related ced-3/Nedd2-like protein Protein, caspase 8 Protein, caspase-8 Protein, caspase-8-like Protein, caspase 8, apoptosis-related cysteine peptidase Protein, casp8.L Protein, LOC661095 Protein, CASP8 Protein, LOC5563818 Protein, casp8 Protein, LOC100222284 Protein, Casp8 Protein
    Background

    Background: Caspase-8 (Cysteine-aspartic acid protease 8/Casp8a, also named MCH5, FLICA and MACH alpha 1) is a 28 kDa member of the peptidase C14A family of enzymes. It is widely expressed and is considered an initiating caspase for the apoptotic cascade. Caspase-8 a

    Synonym: CASP8_MOUSE, Caspase-8, Casp8,EC:3.4.22.61

    Molecular Weight
    17.27 kDa
    UniProt
    O89110
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
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