IL12 Protein (AA 23-328)
Quick Overview for IL12 Protein (AA 23-328) (ABIN7505595)
Target
See all IL12 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 23-328
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Sequence
- Ile23-Ser328
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Characteristics
- A DNA sequence encoding the Human IL12(P40) Protein(P29460)(23-328)was expressed with a polyhistidine tag at the C-terminus.
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Endotoxin Level
- <1.0 EU per μg of the protein as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. -
Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- IL12 (Interleukin 12 (IL12))
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Alternative Name
- IL12
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Background
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Abbreviation: IL-12
Target Synonym: Interleukin-12 subunit beta,Cytotoxic lymphocyte maturation factor 40 kDa subunit,CLMF p40,IL-12 subunit p40,Il12b,NKSF2
Background: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.
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Molecular Weight
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Calculated MW: 35 kDa
Observed MW: 38 kDa
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UniProt
- P29460
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Pathways
- JAK-STAT Signaling, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
Target
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