ANGPTL4 Protein (His tag)
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- Target See all ANGPTL4 Proteins
- ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ANGPTL4 protein is labelled with His tag.
- Purpose
- Recombinant Human Angiopoietin-like 4/ANGPTL4 Protein
- Specificity
- Pro166-Ser406
- Purity
- > 95 % by SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- < 1 EU/μg of the protein by LAL method.
- Top Product
- Discover our top product ANGPTL4 Protein
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Angiopoietin-Like 4 (ANGPTL4) (AA 166-406) protein (His tag)
ANGPTL4 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Angiopoietin-Like 4 (ANGPTL4) (AA 164-406) protein (His tag)ANGPTL4 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Angiopoietin-Like 4 (ANGPTL4) (AA 26-406) protein (GST tag)ANGPTL4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Angiopoietin-Like 4 (ANGPTL4) (AA 168-410) protein (His tag)ANGPTL4 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Angiopoietin-Like 4 (ANGPTL4) (AA 26-130) protein (GST tag)ANGPTL4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Angiopoietin-Like 4 (ANGPTL4) protein (Fc Tag)ANGPTL4 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Concentration
- 0.8 mg/mL
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
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Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
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- Target
- ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))
- Alternative Name
- Angiopoietin-like 4/ANGPTL4 (ANGPTL4 Products)
- Synonyms
- ANGPTL2 Protein, ARP4 Protein, FIAF Protein, HFARP Protein, NL2 Protein, PGAR Protein, pp1158 Protein, Arp4 Protein, Bk89 Protein, Fiaf Protein, Hfarp Protein, Ng27 Protein, Pgar Protein, Pgarg Protein, Pp1158 Protein, ANGPTL4 Protein, fiaf Protein, im:7144703 Protein, si:rp71-39b20.7 Protein, angiopoietin like 4 Protein, angiopoietin-like 4 Protein, ANGPTL4 Protein, Angptl4 Protein, angptl4 Protein
- Background
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Description: Angiopoietin-related protein 4 ( ANGPTL4 ) is a secreted protein and contains 1 fibrinogen C-terminal domain. The protein may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity). In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.
Name: ANGPTL4,ARP4,FIAF,HARP,HFARP,NL2,PGAR,TGQTL,UNQ171,pp1158
- Gene ID
- 51129
- UniProt
- Q9BY76
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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