FZD2 Protein (Fc Tag,His tag)
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- Target See all FZD2 Proteins
- FZD2 (Frizzled Family Receptor 2 (FZD2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FZD2 protein is labelled with Fc Tag,His tag.
- Purpose
- Recombinant Human Frizzled-2/FZD2 Protein
- Sequence
- QFHGEKGISI PDHGFCQPIS IPLCTDIAYN QTIMPNLLGH TNQEDAGLEV HQFYPLVKVQ CSPELRFFLC SMYAPVCTVL EQAIPPCRSI CERARQGCEA LMNKFGFQWP ERLRCEHFPR HGAEQICVGQ NHSEDGAPAL
- Specificity
- Gln24-Leu163
- Purity
- > 95 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- < 1 EU/μg of the protein by LAL method.
- Top Product
- Discover our top product FZD2 Protein
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Frizzled Family Receptor 2 (FZD2) protein (Fc Tag)
FZD2 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Frizzled Family Receptor 2 (FZD2) (AA 192-245) protein (GST tag)FZD2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Frizzled Family Receptor 2 (FZD2) (AA 24-156) protein (Fc Tag)FZD2 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Frizzled Family Receptor 2 (FZD2) (AA 24-190) protein (Fc Tag)FZD2 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- Target
- FZD2 (Frizzled Family Receptor 2 (FZD2))
- Alternative Name
- Frizzled-2/FZD2 (FZD2 Products)
- Synonyms
- BG01711 Protein, CG9739 Protein, D-Fz2 Protein, D-fz2 Protein, DFZ2 Protein, DFz-2 Protein, DFz2 Protein, Dfrz2 Protein, Dfz2 Protein, Dfz[[2]] Protein, Dm Fz2 Protein, Dmel\\CG9739 Protein, FZ2 Protein, Fz2 Protein, dFz2 Protein, dfz(2) Protein, dfz2 Protein, dfz2r Protein, frz2 Protein, fz-2 Protein, fz8 Protein, zfz2 Protein, zg08 Protein, cb383 Protein, wu:fb70g09 Protein, FZD2 Protein, fzE2 Protein, hFz2 Protein, Fz-10 Protein, Fzd10 Protein, cFz-2 Protein, frizzled2 Protein, fz2 Protein, xfz2 Protein, AL033370 Protein, AW456835 Protein, Fz10 Protein, Mfz10 Protein, Mfz10a Protein, frizzled 2 Protein, frizzled class receptor 2 Protein, frizzled class receptor 2 S homeolog Protein, fz2 Protein, fzd2 Protein, FZD2 Protein, Fzd2 Protein, fzd2.S Protein
- Background
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Description: Frizzled-2 (FZD2) is also known as FzE2, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD2 contains one FZ (frizzled) domain. FZD2 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. The Lys-Thr-X-X-X-Trp motif of FZD2 interacts with the PDZ doman of Dvl (Disheveled) family members and is involved in the activation of the Wnt/beta-catenin signaling pathway.
Name: Fz2, fz-2, fzE2, hFz2, OMOD2,FZD2
- Gene ID
- 2535
- UniProt
- Q14332
- Pathways
- WNT Signaling
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