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GPA33 Protein (His tag)

GPA33 Origin: Human Host: HEK-293 Cells Recombinant > 95 % by SDS-PAGE.
Catalog No. ABIN7520046
  • Target See all GPA33 Proteins
    GPA33 (Glycoprotein A33 (Transmembrane) (GPA33))
    Protein Type
    Recombinant
    Origin
    • 11
    • 3
    • 1
    • 1
    Human
    Source
    • 7
    • 4
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This GPA33 protein is labelled with His tag.
    Purpose
    Recombinant Human Cell surface A33 antigen/GPA33 Protein
    Sequence
    ISVETPQDVL RASQGKSVTL PCTYHTSTSS REGLIQWDKL LLTHTERVVI WPFSNKNYIH GELYKNRVSI SNNAEQSDAS ITIDQLTMAD NGTYECSVSL MSDLEGNTKS RVRLLVLVPP SKPECGIEGE TIIGNNIQLT CQSKEGSPTP QYSWKRYNIL NQEQPLAQPA SGQPVSLKNI STDTSGYYIC TSSNEEGTQF CNITVAVRSP SMNV
    Specificity
    Ile22-Val235
    Purity
    > 95 % by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    < 0.1 EU/μg of the protein by LAL method.
    Top Product
    Discover our top product GPA33 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    Buffer
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • Target
    GPA33 (Glycoprotein A33 (Transmembrane) (GPA33))
    Alternative Name
    Cell surface A33 antigen/GPA33 (GPA33 Products)
    Synonyms
    A33 Protein, 2010310L10Rik Protein, 2210401D16Rik Protein, BB116197 Protein, glycoprotein A33 Protein, glycoprotein A33 (transmembrane) Protein, GPA33 Protein, Gpa33 Protein
    Background

    Description: Cell surface A33 antigen, also known as glycoprotein A33, is a single-pass type I membrane protein which is expressed in normal gastrointestinal epithelium and in 95 % of colon cancers. GPA33 contains one Ig-like C2-type (immunoglobulin-like) domain and one Ig-like V-type (immunoglobulin-like) domain. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. Intracellular traffic and recycling to the cell surface appear to play a major role in GPA33 function and to have an influence on its surface density superseding translational regulation.

    Name: A33,GPA33

    Gene ID
    10223
    UniProt
    Q99795
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