IFNW1 Protein (His tag)
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- Target See all IFNW1 (IFNW) Proteins
- IFNW1 (IFNW) (Interferon, omega 1 (IFNW))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IFNW1 protein is labelled with His tag.
- Purpose
- Active Recombinant Human Interferon omega-1/IFNW1 Protein
- Sequence
- GCDLPQNHGL LSRNTLVLLH QMRRISPFLC LKDRRDFRFP QEMVKGSQLQ KAHVMSVLHE MLQQIFSLFH TERSSAAWNM TLLDQLHTGL HQQLQHLETC LLQVVGEGES AGAISSPALT LRRYFQGIRV YLKEKKYSDC AWEVVRMEIM KSLFLSTNMQ ERLRSKDRDL GSS
- Specificity
- Gly23-Ser195
- Purity
- > 97 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- < 0.1EU/μg
- Biological Activity Comment
- Measured in a cell cytotoxicity assay using TF-1 cells. The ED50 for this effect is 0.13-0.54 ng/mL.
- Top Product
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Interferon, omega 1 (IFNW) (AA 24-195) protein (His tag)
IFNW Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Interferon, omega 1 (IFNW) (AA 1-195) protein (GST tag)IFNW Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Interferon, omega 1 (IFNW) (AA 22-104) protein (GST tag)IFNW Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Interferon, omega 1 (IFNW) (AA 22-195) protein (His tag)Crystallography grade IFNW Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Concentration
- 0.7 mg/mL
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- Target
- IFNW1 (IFNW) (Interferon, omega 1 (IFNW))
- Alternative Name
- Interferon omega-1/IFNW1 (IFNW Products)
- Synonyms
- IFNW1 Protein, interferon omega 1 Protein, interferon, omega 1 Protein, inteferon omega 1 Protein, IFNW1 Protein, LOC100155760 Protein, IFN-OMEGA1 Protein
- Background
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Description: IFNs are a large family of proteins having antiviral, antiproliferative, and immunomodulatory effects, and are divided into two major classes, type I and type II, based on differences in receptor binding and nucleotide sequence. Type I IFNs consist of IFN α, β, τ, and ω and bind to the type I IFN receptor, whereas IFN-γ is the only type II IFN and is specific for the type II IFN receptor. Human IFN-ω, was identified by three independent groups in 1985 and is structurally related to IFN-α and -β. Both human IFN-ω and IFN-α are produced by virally induced leukocytes and have similar antiviral activities on human cell lines, and a sizeable proportion (at least 1 % ) of the total antiviral activity of leukocyte IFN is contributed by IFN-ωl. Also, it was reported that IFN-ω could inhibit the growth of human tumors in vivo.
Name: Interferon omega-1,IFNW1
- Gene ID
- 3467
- UniProt
- P05000
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