Kallikrein 8 Protein (KLK8) (His tag)
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- Target See all Kallikrein 8 (KLK8) Proteins
- Kallikrein 8 (KLK8)
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Kallikrein 8 protein is labelled with His tag.
- Purpose
- Active Recombinant Human Kallikrein-8/KLK8 Protein
- Sequence
- QEDKVLGGHE CQPHSQPWQA ALFQGQQLLC GGVLVGGNWV LTAAHCKKPK YTVRLGDHSL QNKDGPEQEI PVVQSIPHPC YNSSDVEDHN HDLMLLQLRD QASLGSKVKP ISLADHCTQP GQKCTVSGWG TVTSPRENFP DTLNCAEVKI FPQKKCEDAY PGQITDGMVC AGSSKGADTC QGDSGGPLVC DGALQGITSW GSDPCGRSDK PGVYTNICRY LDWIKKIIGS KG
- Specificity
- Gln29-Gly260
- Purity
- > 95 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- < 0.1 EU/μg of the protein by LAL method.
- Biological Activity Comment
- Measured by its ability to cleave the fluorogenic peptide substrate Boc-VPR-AMC. The specific activity is >44.95 pmol/min/μg.
- Top Product
- Discover our top product KLK8 Protein
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Kallikrein 8 (KLK8) (AA 33-260) protein (His tag)
KLK8 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Kallikrein 8 (KLK8) (AA 33-260) protein (His-IF2DI Tag)KLK8 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Kallikrein 8 (KLK8) (AA 97-204) protein (GST tag)KLK8 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Kallikrein 8 (KLK8) (AA 1-260) protein (GST tag)KLK8 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Kallikrein 8 (KLK8) (Active) protein (His tag)KLK8 Origin: Human Host: HEK-293 Cells Recombinant > 98 % as determined by reducing SDS-PAGE. Active
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.
- Storage
- -20 °C,-80 °C
- Storage Comment
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Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
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- Target
- Kallikrein 8 (KLK8)
- Alternative Name
- Kallikrein-8/KLK8 (KLK8 Products)
- Synonyms
- HNP Protein, NP Protein, NRPN Protein, PRSS19 Protein, TADG14 Protein, bsp1 Protein, KLK8 Protein, BSP1 Protein, Nrpn Protein, Prss19 Protein, kallikrein related peptidase 8 Protein, kallikrein related-peptidase 8 Protein, KLK8 Protein, Klk8 Protein
- Background
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Description: Kallikrein-8, also known as Neuropsin, Serine protease 19, Serine protease TADG-14, Tumor-associated differentially expressed gene 14 protein and KLK8, is a secreted protein which belongs to the peptidase S1 family and Kallikrein subfamily. It is a serine protease which is capable of degrading a number of proteins such as casein, fibrinogen, kininogen, fibronectin and collagen type IV. Kallikrein-8 / KLK8 is involved in skin desquamation and keratinocyte proliferation and plays a role in the secondary phase of pathogenesis following spinal cord injury. Kallikrein-8 / KLK8 is expressed at high levels in serum, ascites fluid and tumor cytosol of advanced stage ovarian cancer patients and may serve as a marker of ovarian cancer.
Name: KLK8, HNP, NP, NRPN, PRSS19, TADG14, kallikrein-8,Kallikrein 8,HNP,NP,NRPN,PRSS19,TADG14
- Gene ID
- 11202
- UniProt
- O60259
- Pathways
- Complement System
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