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LAMP1 Protein (His tag)

LAMP1 Origin: Human Host: HEK-293 Cells Recombinant > 97 % by SDS-PAGE. Active
Catalog No. ABIN7534641
  • Target See all LAMP1 Proteins
    LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 11
    • 4
    • 1
    Human
    Source
    • 6
    • 4
    • 3
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This LAMP1 protein is labelled with His tag.
    Purpose
    Active Recombinant Human LAMP-1/CD107a Protein
    Sequence
    AMFMVKNGNG TACIMANFSA AFSVNYDTKS GPKNMTFDLP SDATVVLNRS SCGKENTSDP SLVIAFGRGH TLTLNFTRNA TRYSVQLMSF VYNLSDTHLF PNASSKEIKT VESITDIRAD IDKKYRCVSG TQVHMNNVTV TLHDATIQAY LSNSSFSRGE TRCEQDRPSP TTAPPAPPSP SPSPVPKSPS VDKYNVSGTN GTCLLASMGL QLNLTYERKD NTTVTRLLNI NPNKTSASGS CGAHLVTLEL HSEGTTVLLF QFGMNASSSR FFLQGIQLNT ILPDARDPAF KAANGSLRAL QATVGNSYKC NAEEHVRVTK AFSVNIFKVW VQAFKVEGGQ FGSVEECLLD ENSM
    Specificity
    Ala29-Met382
    Purity
    > 97 % by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    < 0.1 EU/μg of the protein by LAL method.
    Biological Activity Comment
    Measured by its binding ability in a functional ELISA. Immobilized Human LAMP1 at 1 μg/mL (100 μL/well) can bind LAMP1 Rabbit pAb with a linear range of 1-8.5 ng/mL.
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  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    Buffer
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • Target
    LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
    Alternative Name
    LAMP-1/CD107a (LAMP1 Products)
    Synonyms
    CD107a Protein, LAMPA Protein, LGP120 Protein, AI196048 Protein, Lamp-1 Protein, LEP100 Protein, LAMP-1 Protein, LGP-A Protein, Lgpa Protein, Lysosome-associated membrane protein 1 Protein, cd107a Protein, lamp-1 Protein, lamp1 Protein, lampa Protein, lgp120 Protein, rexp76 Protein, lysosomal associated membrane protein 1 Protein, lysosomal-associated membrane protein 1 Protein, lysosomal-associated membrane protein 1 L homeolog Protein, LAMP1 Protein, Lamp1 Protein, lamp1.L Protein
    Background

    Description: Lysosomal associated membrane protein 1 (LAMP1), also known as CD107a, is a single-pass type I membrane protein which belongs to the LAMP family.LAMP-1 is a glycoprotein highly expressed in lysosomal membranes.This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. LAMP-1 acts as a receptor for Lassa virus protein. LAMP1 is presented on the plasma membrane during the activation of NK cells, CD8+ T cells, mast cells, basophils, monocytes, and platelets.

    Name: LAMP1, CD107a, LAMPA, LGP120, lysosomal associated membrane protein 1,CD107a,LAMPA,LGP120

    Gene ID
    3916
    UniProt
    P11279-1
    Pathways
    Autophagy
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