MOG Protein (AA 30-154) (His tag)
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- Target See all MOG Proteins
- MOG (Myelin Oligodendrocyte Glycoprotein (MOG))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 30-154
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This MOG protein is labelled with His tag.
- Purpose
- Recombinant Human Myelin Oligodendrocyte Glycoprotein/MOG (C-6His)
- Sequence
- GQFRVIGPRH PIRALVGDEV ELPCRISPGK NATGMEVGWY RPPFSRVVHL YRNGKDQDGD QAPEYRGRTE LLKDAIGEGK VTLRIRNVRF SDEGGFTCFF RDHSYQEEAA MELKVEDPFY WVSPGVDHHH HHH
- Characteristics
- Recombinant Human Myelin-Oligodendrocyte Glycoprotein/MOG is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Gly30-Gly154) of Human MOG fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product MOG Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - Expiry Date
- 3 months
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- Target
- MOG (Myelin Oligodendrocyte Glycoprotein (MOG))
- Alternative Name
- Myelin-oligodendrocyte-glycoprotein (MOG Products)
- Synonyms
- MOGIG2 Protein, NRCLP7 Protein, B230317G11Rik Protein, MOG Protein, myelin oligodendrocyte glycoprotein Protein, MOG Protein, Mog Protein
- Sub Type
- Fusionprotein
- Background
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Myelin Oligodendrocyte Glycoprotein (MOG) is a transmembrane protein, which is expressed exclusively in the CNS. MOG contains a single Ig-domain exposed to the extracellular space which allows autoantibodies easy access. MOG protein has been identified as a crucial autoantigen for multiple sclerosis in humans. MOG is capable to produce a demyelinating multiple sclerosis-like disease in experimental animals,namely experimental autoimmune encephalomyelitis (EAE) in rodents and monkeys.
Alternative Names: Myelin-Oligodendrocyte Glycoprotein, MOG - Molecular Weight
- 15.31 kDa
- UniProt
- Q16653
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