SPINK4 Protein (His tag)
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- Target See all SPINK4 Proteins
- SPINK4 (Serine Peptidase Inhibitor, Kazal Type 4 (SPINK4))
- Protein Type
- Recombinant
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SPINK4 protein is labelled with His tag.
- Purpose
- Recombinant Mouse SPINK4 Protein
- Sequence
- GSLVFPRMPF CEHMAELPNC PQTPNLICGT DGLTYENECH LCLTRMKTMK DIQIMKDGQC
- Specificity
- Gly27-Cys86
- Purity
- > 95 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- <0.1EU/μg
- Top Product
- Discover our top product SPINK4 Protein
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Serine Peptidase Inhibitor, Kazal Type 4 (SPINK4) protein (Fc Tag)
SPINK4 Origin: Mouse Host: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE
Serine Peptidase Inhibitor, Kazal Type 4 (SPINK4) (AA 27-86) protein (His tag)Crystallography grade SPINK4 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
Serine Peptidase Inhibitor, Kazal Type 4 (SPINK4) (AA 27-86) protein (His tag)Crystallography grade SPINK4 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- Target
- SPINK4 (Serine Peptidase Inhibitor, Kazal Type 4 (SPINK4))
- Alternative Name
- SPINK4 (SPINK4 Products)
- Synonyms
- PEC-60 Protein, PEC60 Protein, MPGC60 Protein, serine peptidase inhibitor, Kazal type 4 Protein, SPINK4 Protein, Spink4 Protein
- Background
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Description: Serine protease inhibitor Kazal-type 4, also known as Peptide PEC-6 homolog and SPINK4, is a secreted protein that contains one Kazal-like domain. SPINK4 is a member of the SPINK protein family. The gene family of serine protease inhibitors of the Kazal type (SPINK) are functional and positional candidate genes for celiac disease (CD). SPINK1 plays an important role in protecting the pancreas against excessive trypsinogen activation. It is a potent natural inhibitor of pancreatic trypsin activity. SPINK1 mutations are associated with the development of acute and chronic pancreatitis and have been detected in all forms of chronic pancreatitis. SPINK2 functions as a trypsin/acrosin inhibitor and is synthesized mainly in the testis and seminal vesicle where its activity is engaged infertility. The SPINK2 protein contains a typical Kazal domain composed by six cysteine residues forming three disulfide bridges. SPINK9 was identified in human skin. Its expression was strong in palmar epidermis, but not detectable or very low in non palmoplantar skin.
Name: SPINK4,MPGC60,SPINK4
- Gene ID
- 20731
- UniProt
- O35679
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