WIF1 Protein (Gln166Lys) (His tag)
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- Target See all WIF1 Proteins
- WIF1 (WNT Inhibitory Factor 1 (WIF1))
- Protein Type
- Recombinant
- Protein Characteristics
- Gln166Lys
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This WIF1 protein is labelled with His tag.
- Purpose
- Recombinant Human WIF-1(Q166K) Protein
- Sequence
- GPPQEESLYL WIDAHQARVL IGFEEDILIV SEGKMAPFTH DFRKAQQRMP AIPVNIHSMN FTWQAAGQAE YFYEFLSLRS LDKGIMADPT VNVPLLGTVP HKASVVQVGF PCLGKQDGVA AFEVDVIVMN SEGNTILKTP QNAIFFKTCQ QAECPGGCRN GGFCNERRIC ECPDGFHGPH CEKALCTPRC MNGGLCVTPG FCICPPGFYG VNCDKANCST TCFNGGTCFY PGKCICPPGL EGEQCEISKC PQPCRNGGKC IGKSKCKCSK GYQGDLCSKP VCEPGCGAHG TCHEPNKCQC QEGWHGRHCN KRYEASLIHA LRPAGAQLRQ HTPSLKKAEE RRDPPESNYI W
- Specificity
- Gly29-Trp379(Q166K)
- Purity
- > 97 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- < 0.1 EU/μg of the protein by LAL method.
- Top Product
- Discover our top product WIF1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of 20 mM HAc-NaAc,150 mM NaCl,0.5 % CHAPS, pH 6.0.
- Storage
- -20 °C,-80 °C
- Storage Comment
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Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
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- Target
- WIF1 (WNT Inhibitory Factor 1 (WIF1))
- Alternative Name
- WIF-1 (WIF1 Products)
- Synonyms
- shf Protein, GB10372 Protein, wif-1 Protein, WIF1 Protein, WIF-1 Protein, AW107799 Protein, zgc:110507 Protein, protein shifted Protein, wnt inhibitory factor 1 Protein, WNT inhibitory factor 1 Protein, Wnt inhibitory factor 1 Protein, WNT inhibitory factor 1 S homeolog Protein, LOC552805 Protein, CpipJ_CPIJ003761 Protein, wif1 Protein, WIF1 Protein, Wif1 Protein, LOC100511326 Protein, wif1.S Protein
- Background
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Description: WIF (Wnt Inhibitory Factor) is a secreted protein that binds to Wnt proteins and inhibits their activity. WIF is extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation.. WIF-1 is implicated as an early event tumor suppressor in cancers of the prostate, breast, lung and bladder. However, WIF-1's role in carcinogenesis may not be that simple since in other cancer types, such as colon adenocarcinoma, WIF facilitates tumorigenesis.
Name: WIF-1,WIF1
- Gene ID
- 11197
- UniProt
- Q9Y5W5
- Pathways
- WNT Signaling, Positive Regulation of fat Cell Differentiation
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