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CD70 Protein (Fc Tag)

This Recombinant CD70 protein is expressed in Mammalian Cells.
Catalog No. ABIN7538175

Quick Overview for CD70 Protein (Fc Tag) (ABIN7538175)

Target

See all CD70 Proteins
CD70 (CD70 Molecule (CD70))

Protein Type

Recombinant

Origin

  • 34
  • 10
  • 1
  • 1
  • 1
Mouse

Source

  • 27
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Mammalian Cells

Purity

The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
  • Purification tag / Conjugate

    This CD70 protein is labelled with Fc Tag.

    Purpose

    Recombinant mouse CD70 protein with N-terminal human Fc tag

    Specificity

    HFc (Glu99-Ala330) Mouse CD70 (Ser45-Pro195)

    Characteristics

    Extracellular Domain Protein

    Purification

    Purified from cell culture supernatant by affinity chromatography
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    Expiry Date

    12 months
  • Target

    CD70 (CD70 Molecule (CD70))

    Alternative Name

    CD70

    Background

    Predicted to enable cytokine activity and protease binding activity. Predicted to be involved in several processes, including B cell proliferation, T cell mediated immunity, and extrinsic apoptotic signaling pathway. Predicted to be located in extracellular space and membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in Meckel's cartilage, hip, and skeleton. Human ortholog(s) of this gene implicated in lymphoproliferative syndrome. Orthologous to human CD70 (CD70 Molecule). [provided by Alliance of Genome Resources, Apr 2022]

    Molecular Weight

    predicted molecular mass of 42.8 kDa after removal of the signal peptide. The apparent molecular mass of hFc-mCD70 is 35-70 kDa due to glycosylation.

    UniProt

    O55237

    Pathways

    Cancer Immune Checkpoints
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