EGF Protein
Quick Overview for EGF Protein (ABIN7849715)
Target
See all EGF ProteinsProtein Type
Origin
Source
Application
Purity
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Purpose
- Recombinant Human EGF Protein
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- <0.01EU/μg by LAL test
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration <100 μg/mL.)
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,200 mMNaCl,4 % Mannitol, pH 8.0.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
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- EGF (Epidermal Growth Factor (EGF))
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Alternative Name
- EGF
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Background
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Synonyms: Epidermal growth factor,EGF, HOMG4, URG,epithelial growth factor
Description: Recombinant human EGF is produced by the E.coli system, with the target gene encoding Asn971-Arg1023 expressed.
Background: Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. Human EGF is 6- kDaand has 53 amino acid residues and three intramolecular disulfide bonds.EGF was originally described as a secreted peptide found in the submaxillary glands of mice and in human urine. EGF has since been found in many human tissues, including platelets,submandibular gland (submaxillary gland),and parotid gland.Initially, human EGF was known as urogastrone.
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UniProt
- P01133
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Pathways
- NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation
Target
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