NGFB Protein

Catalog No. ABIN7849726

This Recombinant NGFB protein is produced in Escherichia coli (E. coli).

Quick Overview for NGFB Protein (ABIN7849726)

Target: NGFB (Nerve Growth Factor beta (NGFB))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: >95 % by SDS-PAGE

Product Details

Purpose: Recombinant Human Beta-NGF Protein

Sterility: 0.2 μm filtered

Endotoxin Level: <0.01 EU/μg by LAL test

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.

Target Details

Target: NGFB (Nerve Growth Factor beta (NGFB))

Alternative Name: Beta-NGF

Background:

Synonyms: Beta-Nerve Growth Factor,Beta-NGF,NGF,NGFB,β-NGF

Description: Recombinant human Beta-NGF is produced by the E.coli system, with the target gene encoding Ser122-Ala241 expressed.

Background: β-NGF, also known as mature or functional NGF, is produced after degradation of the signaling peptide and proteolytic cleavage of pro-NGF at Ser122. β-NGF homodimerizes and induces neurotropic signaling through tropomyosin-related kinase A (TrkA) and the p75 neurotrophin receptor (p75NTR).

UniProt: P01138

Pathways: NF-kappaB Signaling, RTK Signaling, Regulation of Cell Size