IL-6 Protein
Quick Overview for IL-6 Protein (ABIN7957046)
Target
See all IL-6 (IL6) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Purpose
- Recombinant Human Interleukin-6 protein(IL6) (Active)
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Sequence
- VPPGEDSKDV AAPHRQPLTS SERIDKQIRY ILDGISALRK ETCNKSNMCE SSKEALAENN LNLPKMAEKD GCFQSGFNEE TCLVKIITGL LEFEVYLEYL QNRFESSEEQ ARAVQMSTKV LIQFLQKKAK NLDAITTPDP TTNASLLTKL QAQNQWLQDM TTHLILRSFK EFLQSSLRAL RQM
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Sterility
- 0.2 μm filtered
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Biological Activity Comment
- Assay #1: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using IL-6-dependent murine 7TD1 cells is less than 0.1 ng,ml, corresponding to a specific activity of > 1.0 107 IU,mg. Assay #2: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using IL-6-dependent murine T1165 cells is less than 0.8 ng,ml, corresponding to a specific activity of > 1.25 106 IU,mg.
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Interleukin 6 (IL6) (AA 30-212) protein (His tag,mFc Tag)
IL6 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. IA, ADA, AM, ScA
Interleukin 6 (IL6) (AA 30-212) (Active) proteinIL6 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC Active
Interleukin 6 (IL6) (AA 28-212) (Active) protein (His tag)IL6 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 6 (IL6) (AA 29-212) (Active) proteinIL6 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS-PAGE analysis. Active
Interleukin 6 (IL6) (AA 25-211) (Active) protein (His tag)IL6 Origin: Mouse Host: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Interleukin 6 (IL6) (AA 30-212) (Active) protein (His tag)IL6 Origin: Human Host: HEK-293 Cells > 97 % AcA, CC Active
Interleukin 6 (IL6) (AA 30-212) (Active) proteinIL6 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 6 (IL6) (AA 1-212) protein (GST tag)IL6 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 6 (IL6) (Active) proteinIL6 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 90 % as determined by SDS-PAGE Active
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Comment
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20.7 kDa
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.2 um filtered PBS, pH 7.4. ,lyophilized
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Handling Advice
- Repeated freezing and thawing is not recommended
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
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The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C,-80°C. The shelf life of lyophilized form is 12 months at -20°C,-80°C.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. -
Expiry Date
- 12 months
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- IL-6 (IL6) (Interleukin 6 (IL6))
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Alternative Name
- Interleukin-6
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Molecular Weight
- 20.7 kDa
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Gene ID
- 3569
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UniProt
- P05231
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Pathways
- TLR Signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
Target
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