IL-6 Protein
Quick Overview for IL-6 Protein (ABIN7956075)
Target
See all IL-6 (IL6) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Purpose
- Recombinant Rhesus Macaque Interleukin-6
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Sequence
- MAPVLPGEDS KNVAAPHSQP LTSSERIDKH IRYILDGISA LRKETCNRSN MCESSKEALA ENNLNLPKMA EKDGCFQSGF NEDTCLVKII TGLLEFEVYL EYLQNRFESS EEQARAVQMS TKVLIQFLQK KAKNLDAITT PEPTTNASLL TKLQAQNQWL QDMTTHLILR SFKEFLQSNL RALRQM
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- Less than 1 EU/ug of rRhIL-6 as determined by LAL method.
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Biological Activity Comment
- Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay usingIL-6-dependent murine 7TD1 cells is less than 0.1 ng/ml, corresponding to a specific activity of > 1.0 x107 IU/mg.
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Interleukin 6 (IL6) (AA 30-212) protein (His tag,mFc Tag)
IL6 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. IA, ADA, AM, ScA
Interleukin 6 (IL6) (AA 30-212) (Active) proteinIL6 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC Active
Interleukin 6 (IL6) (AA 28-212) (Active) protein (His tag)IL6 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 6 (IL6) (AA 29-212) (Active) proteinIL6 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS-PAGE analysis. Active
Interleukin 6 (IL6) (AA 25-211) (Active) protein (His tag)IL6 Origin: Mouse Host: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Interleukin 6 (IL6) (AA 1-212) protein (GST tag)IL6 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 6 (IL6) (Active) proteinIL6 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 90 % as determined by SDS-PAGE Active
Interleukin 6 (IL6) (AA 25-211) (Active) protein (His tag)IL6 Origin: Rat Host: Baculovirus infected Insect Cells Recombinant > 95 % SDS, AcA Active
Interleukin 6 (IL6) (AA 30-212) (Active) protein (His tag)IL6 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, AcA Active
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Comment
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Approximately 21.1 kDa, a single non-glycosylated polypeptide chain containing 186 amino acids.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from a 0.2 um filtered concentrated solution in 50 mM Tris-HCl, pH 9.0, 600 mM NaCl, with 0.02 % Tween-20.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
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Expiry Date
- 12 months
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- IL-6 (IL6) (Interleukin 6 (IL6))
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Alternative Name
- Interleukin-6
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Molecular Weight
- 21.1 kDa
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Pathways
- TLR Signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
Target
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