TNF alpha Protein
Quick Overview for TNF alpha Protein (ABIN7937241)
Target
See all TNF alpha ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Purpose
- Recombinant Human Tumor Necrosis Factor-alpha/TNFSF2, Variant
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Sequence
- MRKRKPVAHV VANPQAEGQL QWLNRRANAL LANGVELRDN QLVVPSEGLY LIYSQVLFKG QGCPSTHVLL THTISRIAVS YQTKVNLLSA IKSPCQRETP EGAEAKPWYE PIYLGGVFQL EKGDRLSAEI NRPDYLDFAE SGQVYFGIIA F
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- Less than 1 EU/ug of rHu TNF-alpha/TNFSF2, Variant as determined by LAL method.
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Biological Activity Comment
- Fully biologically active when compared to standard. The ED50 as determined by a cytotoxicity assay using murine L929 cells is less than 0.01 ng/ml, corresponding to a specific activity of > 1.0 x107 IU/mg in the presence of actinomycin D.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.0.
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- TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
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Alternative Name
- Tumor Necrosis Factor-alpha
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Gene ID
- 7124
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UniProt
- P01375
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Pathways
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome
Target
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