BDNF Protein (AA 129-247)
Quick Overview for BDNF Protein (AA 129-247) (ABIN7937438)
Target
See all BDNF ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 129-247
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Purpose
- Recombinant Human/Murine/Rat/Canine/Equine Brain-derived Neurotrophic Factor
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- Less than 0.1 EU/ug of rHu/Mu/Rt/Ca/EqBDNF as determined by LAL method.
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Biological Activity Comment
- Measured in a cell proliferation assay using BaF mouse pro-B cells transfected with TrkB. The ED50 for this effect is 0.2-2 ng/mL. The specific activity of rHu/Mu/Rt/Ca/EqBDNF is approximately 1.3 x 103units/ug, which is calibrated against recombinant human BDNF WHO Standard. Measured by its binding ability in a functional ELISA. When Recombinant Human TrkB Fc Chimera is coated at 1 ug/mL, rHu/Mu/Rt/Ca/EqBDNF binds with an apparent Kd <1 nM.
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Brain-Derived Neurotrophic Factor (BDNF) (Active) protein (Biotin)
BDNF Origin: Human Host: Escherichia coli (E. coli) Recombinant WB, CC, in vivo, Diff, CyTox, AD, FM, IF, LCI Active
Brain-Derived Neurotrophic Factor (BDNF) (AA 1-255) protein (GST tag)BDNF Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Brain-Derived Neurotrophic Factor (BDNF) (AA 1-247) protein (GST tag)BDNF Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Brain-Derived Neurotrophic Factor (BDNF) proteinBDNF Origin: Human Host: Escherichia coli (E. coli) Recombinant 97,00% SDS
Brain-Derived Neurotrophic Factor (BDNF) (AA 137-237), (partial) protein (GST tag)BDNF Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % SDS, ELISA
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Comment
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Apparent molecular mass of 13-14 kDa in SDS-PAGE under reducing conditions, a single glycosylated polypeptide protein consisting of 119 amino acids.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from 0.2 um filtered concentrated solution in 100 mM Sodium Citrate and 300 mM NaCl, pH 3.0.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
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Expiry Date
- 12 months
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- BDNF (Brain-Derived Neurotrophic Factor (BDNF))
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Alternative Name
- Brain-derived Neurotrophic Factor
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Molecular Weight
- 14 kDa
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UniProt
- P23560
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Pathways
- RTK Signaling, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
Target
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