IL-2 Protein
Quick Overview for IL-2 Protein (ABIN8057021)
Target
See all IL-2 (IL2) ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Purpose
- Recombinant Human Interleukin-2/IL-2 Protein (active)
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Sequence
- Ala 21-Thr 153
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- ≤0.01 EU per μg by the LAL method.
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Biological Activity Comment
- Human IL-2 Protein, Tag Free stimulates proliferation of CTLL-2 cells. The specific activity of Human IL-2 Protein, Tag Free is > 0.60 x 10^7 IU/mg, which is calibrated against human IL-2 WHO International Standard.
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Interleukin 2 (IL2) (AA 21-153) (Active) protein
IL2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 2 (IL2) protein (His tag)IL2 Origin: Human Host: HEK-293 Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE. ScA, IA, ADA, AM
Interleukin 2 (IL2) (AA 21-153) protein (mFc Tag)IL2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM
Interleukin 2 (IL2) (AA 21-169) (Active) protein (Biotin,His-Avi Tag)IL2 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Interleukin 2 (IL2) (AA 21-169) (Active) protein (His-Avi Tag)IL2 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 2 (IL2) (Active) proteinIL2 Origin: Rat Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 2 (IL2) (AA 21-153) protein (His tag)IL2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM
Interleukin 2 (IL2) (AA 21-153) (Active) proteinIL2 Origin: Human Host: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Interleukin 2 (IL2) (AA 21-169) (Active) proteinIL2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE. CC Active
Interleukin 2 (IL2) (AA 21-153) (Active) protein (Fc Tag,AVI tag,Biotin)IL2 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4 with trehalose as protectant.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- IL-2 (IL2) (Interleukin 2 (IL2))
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Alternative Name
- Interleukin-2
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Background
- Interleukin-2,IL-2,T-Cell Growth Factor,TCGF,Aldesleukin,Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system,belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.
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Molecular Weight
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Calculated MW: 15.4 kDa
Observed MW: 14-22 kDa
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UniProt
- P60568-1
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Pathways
- JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
Target
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